48 Hours in Rome: The Ultimate Weekend Itinerary
- Ian Carter
- Aug 17
- 2 min read
Updated: Nov 9
Rome, the Eternal City, is a perfect mix of history, culture, and Italian cuisine. Even with just 48 hours, you can experience iconic landmarks, wander charming piazzas, and indulge in authentic Roman food. Here’s your weekend itinerary to make the most of your short city break.

Day 1: Ancient Rome and Iconic Landmarks
Morning – Colosseum & Roman Forum
Start your trip with the Colosseum, the world-famous amphitheater. Book tickets in advance to skip the lines and explore this symbol of Rome’s ancient power. Just a short walk away, explore the Roman Forum, where you’ll see ruins of temples, arches, and government buildings.
Afternoon – Pantheon & Piazza Navona
After lunch, visit the Pantheon, one of the best-preserved ancient buildings in Rome. Then, take a stroll to Piazza Navona, famous for its Baroque fountains and lively atmosphere. Stop for a gelato while enjoying street performances.
Evening – Trevi Fountain & Trastevere
As the sun sets, toss a coin into the Trevi Fountain to ensure your return to Rome. Finish the evening in Trastevere, Rome’s charming neighborhood full of cobbled streets, cozy trattorias, and vibrant nightlife.

Day 2: Vatican City & Panoramic Views
Morning – Vatican Museums & St. Peter’s Basilica
Start early at the Vatican Museums, home to the Sistine Chapel. Finish your tour with a visit to St. Peter’s Basilica, marveling at Michelangelo’s Pietà and the grand dome.
Afternoon – Castel Sant’Angelo & Spanish Steps
Walk along the Tiber River to Castel Sant’Angelo. Then, climb the Spanish Steps for fantastic city views. Stop nearby for espresso and pastries to recharge.
Evening – Sunset at Gianicolo Hill & Farewell Dinner
End your Roman weekend with panoramic views from Gianicolo Hill. Then, enjoy a farewell dinner in a classic Roman trattoria, sampling carbonara, cacio e pepe, and local wines.

Quick Tips for 48 Hours in Rome
Best Time to Visit: Spring (April–June) or autumn (September–October) for pleasant weather.
Transport: Rome’s metro, buses, and trams are efficient. Consider a 48-hour public transport pass.
Language: Italian is spoken, but English is widely understood in tourist areas.
Safety: Keep an eye on belongings, especially near crowded landmarks like Trevi Fountain and Spanish Steps.
Discovering Roman Cuisine
Rome’s food and drink scene is unforgettable. From traditional trattorias to rooftop cocktail bars, you’ll find plenty to savour. The phrase "authentic Roman food" captures the essence of what to expect in this vibrant city.
Embracing the Roman Atmosphere
As you wander through the streets, take a moment to soak in the atmosphere. The blend of ancient history and modern life creates a unique charm. Each corner reveals a new story, inviting you to explore further.
Final Thoughts
Your 48 hours in Rome will be packed with unforgettable experiences. From the majestic Colosseum to the serene beauty of the Vatican, every moment is a chance to create lasting memories. Enjoy your journey, and remember to take it all in—Rome is waiting for you!










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