48 Hours in Rome: The Ultimate Weekend Itinerary

Rome, the Eternal City, is a perfect mix of history, culture, and Italian cuisine. Even with just 48 hours, you can experience iconic landmarks, wander charming piazzas, and indulge in authentic Roman food. Here’s your weekend itinerary to make the most of your short city break.

Day 1: Ancient Rome and Iconic Landmarks

Morning – Colosseum & Roman Forum

Start your trip with the Colosseum, the world-famous amphitheater. Book tickets in advance to skip the lines and explore this symbol of Rome’s ancient power. Just a short walk away, explore the Roman Forum, where you’ll see ruins of temples, arches, and government buildings.

Afternoon – Pantheon & Piazza Navona

After lunch, visit the Pantheon, one of the best-preserved ancient buildings in Rome, followed by a stroll to Piazza Navona, famous for its Baroque fountains and lively atmosphere. Stop for a gelato while enjoying street performances.

Evening – Trevi Fountain & Trastevere

As the sun sets, toss a coin into the Trevi Fountain to ensure your return to Rome. Finish the evening in Trastevere, Rome’s charming neighborhood full of cobbled streets, cozy trattorias, and vibrant nightlife.

Day 2: Vatican City & Panoramic Views

Morning – Vatican Museums & St. Peter’s Basilica

Start early at the Vatican Museums, home to the Sistine Chapel. Finish your tour with a visit to St. Peter’s Basilica, marveling at Michelangelo’s Pietà and the grand dome.

Afternoon – Castel Sant’Angelo & Spanish Steps

Walk along the Tiber River to Castel Sant’Angelo, then climb the Spanish Steps for fantastic city views. Stop nearby for espresso and pastries to recharge.

Evening – Sunset at Gianicolo Hill & Farewell Dinner

End your Roman weekend with panoramic views from Gianicolo Hill, then enjoy a farewell dinner in a classic Roman trattoria, sampling carbonara, cacio e pepe, and local wines.

Quick Tips for 48 Hours in Rome

• Best Time to Visit: Spring (April–June) or autumn (September–October) for pleasant weather.

• Transport: Rome’s metro, buses, and trams are efficient. Consider a 48-hour public transport pass.

• Language: Italian is spoken, but English is widely understood in tourist areas.

• Safety: Keep an eye on belongings, especially near crowded landmarks like Trevi Fountain and Spanish Steps.

Hungry for More?

Rome’s food and drink scene is unforgettable. From traditional trattorias to rooftop cocktail bars, you’ll find plenty to savour.

For our top restaurants and bars in Rome, follow this link.